2020-07-07 18:11:00

Novavax Inc., one of the front-runners in the race to develop a Covid-19 vaccine, will receive $1.6 billion from the US government, the biggest contribution yet from the Operation Warp Speed program.

The funds will allow the company to conduct advanced human studies and establish manufacturing to deliver 100 million doses as soon as late 2020, Gaithersburg, Maryland-based Novavax said in a statement. The shares rose 32% in premarket trading.

Novavax is among companies striving to develop an inoculation against the novel coronavirus that’s spreading quickly in countries including the US, India and Mexico. President Donald Trump’s Warp Speed program has backed efforts at a number of companies, including Johnson & Johnson, Merck & Co., Pfizer Inc., Moderna Inc. and AstraZeneca Plc, to get doses as early as possible.

Operation Warp Speed seeks to compress a process that is typically years long into a matter of months. The drive is being led by General Gustave Perna, who directs the US Army Materiel Command, and former GlaxoSmithKline Plc executive Moncef Slaoui.

Spike protein

The funds will help Novavax begin a final-stage study of its vaccine candidate as early as this fall, with as many as 30,000 subjects, according to the statement.

The biotech company earlier secured as much as $388 million in May from the Coalition for Epidemic Preparedness Innovations, the single largest contribution from the organization at the time. The company’s vaccine candidate is meant to provoke the production of antibodies that block the “spike” protein the coronavirus uses to infect host cells.

Separately, Regeneron Pharmaceuticals Inc. secured a $450 million award from the program under the auspices of the US Biomedical Advanced Research and Development Authority, or BARDA. The Tarrytown, NY-based company will use the funds to scale up production of an antibody cocktail to prevent infection.

Analysts are expecting results from Regeneron’s antibody program sometime in the third quarter. Novavax plans to report a first look at its vaccine in patients later this month.

Drug companies and university researchers are investigating more than 140 experimental inoculations, according to the World Health Organization. Moderna, Pfizer and the University of Oxford, working with AstraZeneca, are among the companies and institutions that have started studies of their vaccines in healthy patients.

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